Review Article
Year: 2023 | Month: July-September | Volume: 8 | Issue: 3 | Pages: 455-464
DOI: https://doi.org/10.52403/ijshr.20230360
Spatio-temporal Analysis of Hand, Foot and Mouth Disease: A Systematic Review
Thi-Hien Cao1, Thi-Bich-Thuy Luong1, Thi-Tuyet-Mai Nguyen2
1Faculty of Nursing, East Asia University of Technology, Hanoi, Vietnam
2Faculty of Pharmacy, East Asia University of Technology, Hanoi, Vietnam
Corresponding Author: Thi-Hien Cao
ABSTRACT
Background: Hand, foot and mouth disease (HFMD) is a widespread pediatric disease caused primarily by human enterovirus 71 (EV-A71) and Coxsackievirus A16 (CV-A16). Over the past two decades, our understanding of HFMD has greatly improved and it has received significant attention. This study reports a systematic review of spatio-temporal analysis of HFMD.
Materials and Methods: Systematic and comprehensive searches were conducted in the PubMed, Scopus, Web of Science, and Google Scholar. Four different issues related this issue are presented under four sub-sections; including the analysis of spatial-temporal clustering, hotspot and coldspot, spatial-temporal heterogeneity and risk factors
Results: It was found from 64 articles that spatio-temporal analysis can effectively support the study of HFMD such as understanding of spatial patterns, hotspot, the spread and affecting factors.
Conclusion: The spatial-temporal analysis can provide important information and contribute to development of effective measurements to control and prevent its transmission. The study contributes to current research on the spread and affecting factor of HFMD.
Keywords: Spatio-temporal analysis, Spatial autocorrelation, GIS, Spatial patterns, Hand, foot and mouth disease, Review.