Original Research Article
Year: 2023 | Month: July-September | Volume: 8 | Issue: 3 | Pages: 281-290
DOI: https://doi.org/10.52403/ijshr.20230339
Characteristics of the Neutrophil Lymphocyte Ratio in Patients with Neurological Disorders Against Infectious Disease Outcomes During Hospitalization in the Intensive Room of Prof. Dr. I.G.N.G Ngoerah Hospital, Denpasar, Bali from February 2019 to February 2022
Ni Luh Diah Kencana Dewi1, I Wayan Widyantara1, Ida Bagus Kusuma Putra1, Kumara Tini1
1Department of Neurology, Faculty of Medicine, Udayana University/ I.G.N.G Prof Ngoerah Hospital, Bali, Indonesia
Corresponding Author: I Wayan Widyantara
ABSTRACT
Introduction: The neutrophil-lymphocyte ratio (NLR) biomarker is one of the biomarkers used to assess the possible outcome of infection in patients experiencing the acute phase of a disease. Patients with a diagnosis in the field of neurology tend to have the possibility of a long-extended stay, which is closely related to the risk of infection during treatment. Neutrophil- lymphocytes ratio (NLR) examination can provide a quick and easy prognostic estimation, especially in patients with an extended stay in the hospital.
Methods: This study is a descriptive analysis with a retrospective study that describes the characteristics of neurological patients with an infectious outcome through laboratory results of the serum neutrophil-lymphocyte ratio (neutrophil lymphocytes ratio). The data collected were gender, NLR (Neutrophil lymphocytes ratio) parameter sign, and outcome of infectious diseases such as pneumonia, sepsis, meningoencephalitis, and urinary tract infections during treatment with neurological diagnosis as the underlying illness caused the patient to be treated. Samples were taken based on the medical record data of treated patients. They meet the inclusion criteria, which are then processed descriptively through the number and percentage.
Results: A total of 90 research sample data were included in the study, the number of male correspondents was 53 people (58.9%), and women were 37 people (41.1%). Analysis of the research sample data showed that the serum neutrophil-lymphocyte ratio level during treatment in the intensive room was 18.03%, with a standard deviation of 19.9. Of the total patients with pneumonia, 84 people (93.3%), ten people (11.1%) experienced meningoencephalitis during treatment in the intensive room, 66 people (73.3%) had sepsis, and 25 people (27.8 %) had a urinary tract infection with the mean ratio of neutrophil to lymphocyte for the outcome of the disease ranging from 2.3 to 75.1
Conclusion: Patients undergoing treatment in the intensive room of I.G.N.G Prof Ngoerah Hospital from February 2019 to February 2022 tend to experience an increase in the neutrophil-lymphocyte ratio above the average value, which is above 3.13, with an infection outcome during treatment.
This study uses a number of ethical exemptions as follows 2929/UN14.2.2.VII.14/LT/2022
Keywords: Infection Outcome, Neurological abnormalities, Neutrophil lymphocytes ratio (NLR)