Case Report
Year: 2021 | Month: October-December | Volume: 6 | Issue: 4 | Pages: 82-86
DOI: https://doi.org/10.52403/ijshr.20211013
A Case Report on Allergic Reaction to Pantoprazole
Rashi Bahuguna1, Devesh Joshi1, Madhulata Rana2
1Pharm.D. Student, Department of Pharmacy Practice,
Shri Guru Ram Rai Institute of Technology & Science, Dehradun, Uttarakhand, India,
2Professor, Department of Surgery,
Shri Guru Ram Rai Institute of Medical and Health Sciences, Dehradun, Uttarakhand, India
Corresponding Author: Rashi Bahuguna
ABSTRACT
Pantoprazole is a proton pump inhibitor and acts by blocking the gastric pump H+, K-ATPase to inhibit gastric acid secretion. Hypersensitivity reactions due to pantoprazole can be both immediate and delayed hypersensitivity reactions but sometimes it can be a life-threatening anaphylactic reaction. A 64-year female was admitted to the private ward of Shri Mahant Indiresh hospital with chief complaints of 6-7 episodes of vomiting and abdominal pain. Various laboratory tests were performed and the diagnosis was given. After the administration of Injection pantoprazole 40 mg patient developed rashes, itching, vomiting, burning sensation in whole body, restlessness, fever, and chills immediately within few hours. Hypersensitivity reaction to pantoprazole occurred due to Type-1 hypersensitivity reaction. Proton pump inhibitors like pantoprazole decrease gastric pH which increases bacterial growth in the oral cavity and upper GIT. To check on such ADR’s health care professionals should keep an eye on the medication use and its effects and should be cautious while prescribing pantoprazole. Pharmacists should educate the patients regarding possible hypersensitivity reactions from PPIs and how to take these medications to avoid any serious adverse drug reaction.
Keywords: PTCA-Percutaneous transluminal coronary angioplasty, CBC-Complete Blood Count, RFT-Renal Function tests, LFT-Liver function tests, Hb-Hemoglobin, TLC-Total Leucocyte count, PCV-Packed cell volume, RBC-Red Blood Cells, RDW-Red cell distribution width, SGOT-Serum Glutamic oxaloacetic transaminases, ALP-Alkaline phosphatase, GGT-Gamma Glutamyl transferase, PR-Pulse rate, RR-Respiratory rate, BP-Blood Pressure, Temp-Temperature, SpO2-Oxygen saturation.