Original Research Article
Year: 2019 | Month: October-December | Volume: 4 | Issue: 4 | Pages: 70-78
Assessment of Cormic Index in Sickle Cell Disease Subjects and Its Association with Clinical Severity
Dr. Mainak Bardhan1, Ipsita Das2, Romesh Tiwari3, Dr Dnyanesh Amle4, Dr Debapriya Rath5
1House Surgeon, Pt JNM Medical College, Raipur(CG)
2Research Scholar, Department of Biochemistry, Pt JNM Medical College, Raipur (CG))
3MBBS final year, Pt JNM Medical College, Raipur (CG)
4Assistant Professor, Department of Biochemistry, AIIMS, Nagpur
5Assistant Professor, Department of Biochemistry, Pt JNM Medical College, Raipur (CG)
Corresponding Author: Dr Debapriya Rath
ABSTRACT
Sickle cell anemia is a complex pathophysiologic single gene defect genetic disorder with a wide spectrum in the severity of the disease. Decomposing stature into its major components is a useful strategy to assess antecedents of disease, morbidity, and death in adulthood. CORMIC INDEX is calculated as (Sitting Height / Height) × 100. Leg length relative to total body proportions is a good indicator of overall growth reserve capacity of a person or a group of people. Previous studies in sickle cell patients have shown evidence of growth failure and are associated with delayed puberty. There is no study correlating growth pattern in sickle cell disease patients with the CORMIC index, in our study we tried to do this. The main conclusion in which we arrived is that “there is no significant correlation between the severity of sickle cell anemia and cormic index”, however, sickle cell affects many growth parameters i.e. height, weight, and sitting height.
Keywords: Cormic index, Sickle cell Anemia, Hydroxyurea,Chhattisgarh