Case Report
Year: 2019 | Month: April-June | Volume: 4 | Issue: 2 | Pages: 176-178
Ceftriaxone Induced Rash Dermatitis: A Case Report
Vageeshwari Devuni
CMR College Of Pharmacy, Kandlakoya, Medchal road, Hyderabad.
ABSTRACT
Cephalosporins and penicillins are the most widely used antibiotics for the treatment of common infections. Each one has a 4-membereddihydrothiazine beta-lactam ring, but 5-membered dihydrothiazine ring of penicillins is replaced by the 6-membered dihydrothiazine ring in the cephalosporins nucleus. Ceftriaxone, a cephalosporin is used for variety of infections. This drug is known to be associated with rare and mild side-effects such as Urticaria, skin rash, diarrhea, vomiting, transient neutropenia, and hemolysis. Drug hypersensitivity reactions are immunologic responses to medications. Causal relationship between the drug and the reaction is assessed depending on the lag period between the start of the drug and the appearance of the reaction, Antibiotic-related cutaneous drug reactions represent a common cause of dermatological consultations among hospitalised patients, and it is difficult to get the major culprit antibiotic because of the concomitant use of multiple systemic antibiotics. Management of Hypersensitivity reactions: Mild-moderate hypersensitivity reactions are managed by antihistamines and corticosteroids.
Keywords: Ceftriaxone, Rash, Dermatitis, Cephalosporin, Penicillin