Year: 2026 | Month: January-March | Volume: 11 | Issue: 1 | Pages: 101-107
DOI: https://doi.org/10.52403/ijshr.20260111
Detection of Antibacterial Activity of Apple Cider Vinegar against Escherichia Coli Isolated from Patients Visiting Tertiary Care Hospital
Mrunal Bonde1, Deepashri Naik2, Bhagyashree Gawathe3
1PG student, Department of Microbiology, MGM Medical College, and Hospital, Kamothe, MGMIHS, Navi Mumbai, Maharashtra
2Associate Professor, Department of Microbiology, MGM Medical College and Hospital, Kamothe, MGMIHS, Navi Mumbai, Maharashtra
3Tutor & PhD Scholar Microbiology, MGM Medical College and Hospital, Sambhajinagar
Corresponding Author: Dr Deepashri Naik
ABSTRACT
Escherichia coli, a common commensal gut bacterium, can cause severe infections when found outside the digestive tract, including pneumonia, bacteremia, and UTIs. Its presence in hospitals and contaminated food highlights its role in nosocomial and foodborne diseases. The rise of multidrug-resistant (MDR) E. coli, driven by horizontal gene transfer, complicates treatment, necessitating alternative therapies to counter ineffective antibiotics and associated side effects. Apple cider vinegar (ACV) is recognized for its potential health benefits. Its organic acids, particularly acetic acid, exhibit antimicrobial properties by penetrating bacterial cell membranes and causing cell death. Hence, this study was undertaken to detect the antibacterial activity of Apple Cider vinegar with different concentrations against Escherichia coli isolated from patient vising tertiary care hospital. Total number of 250 isolates of E. coli were isolated from the patient's samples like sputum, blood, endotracheal secretions, urine, pus, tissue, wound swab, high vaginal swab and other body fluids. Patient’s age group ranging from 18- 80 years were included in this study, with 113 MDR isolates of E. coli. Maximum isolates were found in ward. Out of 250 Isolates of E. coli maximum isolates showed highest susceptibility to 100% concentration of ACV with mean zone of 25.90 ± 2.41. These findings suggest that apple cider vinegar can be used as an effective adjuvant therapy.
Keywords: Multidrug-Resistant, E. coli, Apple cider vinegar