Year: 2025 | Month: October-December | Volume: 10 | Issue: 4 | Pages: 239-244
DOI: https://doi.org/10.52403/ijshr.20250434
Pulmonary Function Assessment in Non-Alcoholic Fatty Liver Disease Patients - A Comparative Cross-Sectional Study
Sukumar Rajendran1, Shenbagadevi Subramanian2, Leela Priyadharsini Balamurali3
1Assistant Professor, Department of Physiology, Government Medical College & E.S.I Hospital, Coimbatore, Tamil Nadu, India.
2Assistant Professor, Department of Physiology, Government Medical College, Dindigul, Tamil Nadu, India.
3Assistant Professor, Department of Physiology, Dhanalakshmi Srinivasan Institute of Medical Sciences and Hospital, Perambalur, Tamil Nadu, India.
Corresponding Author: Sukumar Rajendran
ABSTRACT
Introduction: Non-communicable diseases have become a major global health burden. Metabolic syndromes, such as diabetes mellitus and hypertension account for a large proportion of non-communicable diseases. Non-alcoholic fatty liver disease (NAFLD) is considered the hepatic manifestation of metabolic syndromes. Numerous studies have shown that individuals with metabolic syndromes experience impaired respiratory function.
Objectives: This study aimed to determine respiratory function in patients with different grades of NAFLD by assessing forced vital capacity (FVC) and forced expiratory volume in 1s (FEV1).
Materials & Methods: This comparative cross-sectional study was conducted on 50 NAFLD patients in a tertiary care hospital in South India. These patients were divided into three severity groups. Severity was assessed and graded by the ultrasound examination. Then the pulmonary function was assessed by measuring FVC and FEV1 using Spirometer. Statistics were done for assessing the correlation between pulmonary function and three different grades of NAFLD.
Results: The measured FVC and FEV1 is significantly lower in NAFLD grade III when compared with NAFLD grade I patients.
Conclusion: This study shows that impairment of respiratory function is more pronounced in patients with increased severity of NAFLD.
Keywords: Non-alcoholic Fatty Liver Disease, Metabolic Syndrome, Respiratory Function Tests, Forced Expiratory Volumes, Spirometry.